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Recombinant Aprotinin EC 3.4.21.9 , aprotinin from bovine lung 5 EPU/mg pro

RTI16

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Description

recombinant aprotinin EC 3.4.21.9,aprotinin from bovine lung 5 EPU/mg pro

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Recombinant Aprotinin / Aprotinin / RTI / rTI / Trypsin Inhibitor

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DESCRIPTION

Recombinant Aprotinin

Aprotinin?is?a?competitive?serine?protease?inhibitor?that?inhibits?trypsin,?chymotrypsin,?kallikrein?and?plasmin.

?Aprotinin?forms?stable?complexes?with?and?blocks?the?active?sites?of?enzymes.?Binding?is?reversible?with?

most?aprotinin-protease?complexes?dissociating?at?pH?>10?or?<3.?Effective?concentration?is?equimolar?with?protease.

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RECOMBINANT,?ANIMAL?COMPONENTS?FREE

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Recombinant?aprotinin?is?expressed?in?E.?Coli,?and?then?purified?with?HPLC.?It?contains?no?animal-derived?components.?This?is?a?recombinant?form?of?the?native,?bovine-

sequence?aprotinin,?which?is?traditionally?isolated?from?bovine?lung?by?methods?involving?fractional?

precipitation,?gel?filtration,?and?ion?exchange?chromatography.?

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? Source? | E.?Coli |
Purified?by | HPLC? |
Physical?form | Liquid?in?0.1?M?NaCl?or?White?lyophilized?powder |
Specific?activity | ≥?5?EPU/mg?pro.? |
Purity | ≥?98%?by?SDS-PAGE |
Contaminant?activity | No?any?other?protease?contaminant.? |
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UNIT?DEFINITION:One?trypsin?inhibitor?unit?(EPU)?will?decrease?the?activity?of?2?trypsin?units?by?50%?where?

one?trypsin?unit?will?hydrolyze?1.0?μmole?of?N-benzoyl-L-arginineethyl?ether(BAEE)?per?sec?at?pH?7.6?at?25?°C.

A?conversion?factor?for?Aprotinin?is:?1?EPU?=?1?USP?Aprotinin?Unit?=?1800?KIU.

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PRODUCT?INFORMATION

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Product | Cat.?No. | Specific?activity | Packaging | Manufacturer |
Recombinant?Aprotinin | RTI16 | ≥?5EPU?/mg?pro | 1mg,10mg,100mg,?or?bulk. | YaxinBio |
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RELATED?PRODUCTS

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Recombinant?trypsin?(Porcine);

Recombinant?trypsin?(Human);

Recombinant?Chymotrypsin;

Recombinant?Carboxypeptidase?B.

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