Chemical Powders
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CAS 13951-70-7 16alpha-Hydroxyprednisolone
Glucocorticoid 16alpha-hydroxyprednisolone White Crystalline Powder Cas 13951-70-7
Product Name: 16alpha-Hydroxyprednisolone
CAS No.: 13951-70-7
EINECS: 237-731-1
Molecular Formula: C21H28O6
Molecular Weight: 376.45
Assay: 98%
Density: 1.381 g/cm3
Melting Point: 235-238 °C
Boiling Point: 591.5 °C at 760 mmHg
Flash Point: 325.6 °C
Storage: Keep it under seal in cool and dark place
Appearance: white crystalline solid
16alpha-hydroxyprednisolone is a C21 steroid that is obtained by hydroxylation of pregnenolone at the C17a position. This step is performed by the mitochondrial cytochrome P450 enzyme 17a-hydroxylase (CYP17A1) that is present in the adrenal and gonads. Peak levels are reached in humans at the end of puberty and then decline. High levels are also achieved during pregnancy. 16alpha-Hydroxyprednisolone is also an advanced intermediate in the synthesis of various corticosteroids such as budesonide and ciclesonide.
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