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Anti Estrogen Steroids Anastrozole / Arimidex For Breast Cancer Treatment 121062-08-6

Anastrozole

Description

Anti Estrogen Steroids Anastrozole/Arimidex Powder Dosage 5mg/ml for Treatment of Breast Cancer? Anastrozole/Arimidex Quick Details What is?Anastrozole/Arimidex??
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? ? It’s lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body. ? It’s used to treat breast cancer in postmenopausal women. It is often given to women whose cancer has progressed even after taking tamoxifen (Nolvadex, Soltamox). ? Its may also be used for purposes not listed in this medication guide. |
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How to use?Anastrozole/Arimidex??

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Recommended dose of Anastrozole:


1. For?men:
Anastrozole has been tested for reducing estrogens, including estradiol, in men. Excess estradiol in men can cause benign prostatic hyperplasia, gynecomastia, and symptoms of hypogonadism. It can also contribute to increased risk of stroke, heart attack, chronic inflammation, prostate enlargement and prostate cancer. Some athletes and body builders use anastrozole as part of their steroid cycle to reduce and prevent symptoms of excess estrogen–gynecomastia, emotional lability and water retention. Study data suggests dosages of 0.5 mg to 1 mg a day reduce serum estradiol approx. 50% in men, which differs in postmenopausal women.


2. For children:
Anastrozole may be used off-label in children with precocious puberty, or children with pubertal gynecomastia.Following the onset of puberty, the epiphyseal plate begins to close due to an increased amount of estrogen production escaping local metabolism and spreading to the circulatory system. It is shown to help slow this process, and increase adult height prediction in adolescent males treated with protein-based peptide hormones for the treatment of growth hormone deficiency.

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Anastrozole/Arimidex?Applications:
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Arimidex is sometimes used to treat male breast cancer, but it has not been well studied in men.Arimidex been studied for use by infertile men to balance testosterone levels and maintain a healthy sperm count.Some male athletes and bodybuilders who take anabolic steroids to build muscle also take Arimidex to reduce the estrogen production that is a side effect of steroid use.

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1, Increasing the time before the cancer comes back in those who experience recurrence |
2, Reducing the risk of the cancer spreading to other parts of the body |
3, Reducing the risk of a new cancer developing in the other breast |
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Anastrozole/Arimidex?Usage:
Arimidex (anastrozole) was the first selective aromatase inhibitor used in bodybuilding, and is still the most popular estrogen control drug. It’s commonly available in liquid form for oral use.
Dosing is typically 0.25, 0.5, or 1.0 mg at a time, at a frequency of once per day or per two days.

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Arimidex is highly suitable for solving either problem. With correctly chosen dosing, free estradiol level can be brought fairly accurately to a desired range. When not using anabolic steroids, for most men I recommend about 20-29 pg/mL for best effect on mood, performance, libido, and long term health and to provide excellent benefit to natural testosterone production.

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Anastrozole has a half life of about two days. For this reason, when use is ongoing, on taking a dose of Arimidex the user will have in his system not only the dose that he just took, but also about another two days’ worth that has built up in his system. If just starting usage, however, there is no such buildup and effect will be less.

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Anastrozole/Arimidex?Specifications :

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COA:
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Items | Standard | Results |
Description | White crystalline powder | Complies |
Identification | IR
HPLC
Reactive | Conform with standard IR
Conform with standard HPLC
Conform |
Solubility | Freely soluble in methanol,acetone,
ethanol and tetrahydrofuran.
And very soluble in acetonitrile | Complies |
Total Impurity | max.0.5% | 0.18% |
Total Unspecified Impurity | max. 0.2% | 0.08% |
Individual unspecified impurlty | max. 0.1% | 0.05% |
Related compound B | max. 0.2% | 0.07% |
Related compound C | max. 0.2% | 0.04% |
Related compound D | max. 0.1% | 0.05% |
Related compound E | max. 0.1% | 0.06% |
Limit of cyclohexane | max. 0.08% | ND |
Limit of ethylacetate | max. 0.1% | 0.07% |
Melting point | 81.0~84.0oC | 82.5~83.2oC |
Water | max. 0.3% | 0.21% |
Residue on ignition | max. 0.1% | 0.07% |
Heavy Metals | max.0.001% | Complies |
Assay(HPLC) | 98.0%~102.0% | 99.8% |
Storage | Cool and dry |
Conclusion | It complies to USP32 . |
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