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Orlistat

96829-58-2

Description

Orlistat

Synonym: N-Formyl-L-leucine (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester;(-)-Tetrahydrolipstatin
CAS:96829-58-2
MF:C29H53NO5
MW:495.73
Assay:99%
Appearance:White powder
Package:foil bag
Key words:Orlistat Orlipastat 96829-58-2 obesity type 2 diabetes weight loss


Medical uses:
Orlistat is used for the treatment of obesity. The amount of weight loss achieved with orlistat varies. In one-year clinical trials, between 35.5% and 54.8% of subjects achieved a 5% or greater decrease in body mass, although not all of this mass was necessarily fat. Between 16.4% and 24.8% achieved at least a 10% decrease in body fat. After orlistat was stopped, a significant number of subjects regained weight-up to 35% of the weight they had lost.

The incidence of type 2 diabetes in an obese population over four years is decreased with orlistat (6.2%) compared to placebo (9.0%).Long-term use of orlistat also leads to a modest reduction in blood pressure (mean reductions of 2.5 and 1.9 mmHg in systolic and diastolic blood pressure respectively).

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Orlistat CAS NO.:96829-58-2
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Orlistat Orlipastat 96829-58-2 obesity type 2 diabetes weight loss, Orlistat Orlipastat 96829-58-2 obesity type 2 diabetes weight loss,

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