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Pactory Price 99% Pure Voglibose CAS 83480-29-9 for??Diabetes Treatment (jerryzhang001@chembj.com)

83480-29-9

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Pactory Price 99% Pure Voglibose CAS 83480-29-9 for??Diabetes Treatment

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Product Name: Voglibose
Synonyms: VOGLIBOSE;3,4-DIDEOXY-4-[[2-HYDROXY-1-(HYDROXYMETHYL)ETHYL]AMINO]-2-C-(HYDROXYMETHYL)-D-EPIINOSITOL;3,4-DIDEOXY-4-[[2-HYDROXY-1-(HYDROXYMETHYL)ETHYL]AMINO]-2-C-(HYDROXYMETHYL)-D-EPINOSITOL;5-(1,3-dihydroxypropan-2-ylamino)-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol;VOGLIBOSE, 99+%;A 71100;AO 128;Basen;

CAS: 83480-29-9;
MF: C10H21NO7;
MW: 267.28.
Description:
Voglibose?(INN?and?USAN, trade name?Voglib, marketed by Mascot Health Series) is an?alpha-glucosidase inhibitor?used for lowering post-prandial blood glucose levels in people with?diabetes mellitus. Voglibose delays the absorption of glucose thereby reducing the risk of macrovascular complications Voglibose was first launched in 1994, under the trade name BASEN, to improve postprandial hyperglycemia in?diabetes mellitus.

Postprandial?hyperglycemia?(PPHG) is primarily due to first phase insulin secretion. Alpha glucosidase inhibitors delay glucose absorption at the intestine level and thereby prevent sudden surge of glucose after a meal.
There are several trials supporting the use of Voglibose in the management of PPHG. Also, it has been established that it is PPHG not FPG which is marker of cardiovascular disorders associated with diabetes. So, controlling PPHG is imperative and Voglibose is indicated for the management of PPHG.

pharmaceutical intermediate, Voglibose ,

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