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Prednisolone

50-24-8

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Description

Prednisolone

Synonyms: 11beta,17alpha,21-Trihydroxypregna-1,4-diene-3,20-dione;1,4-Pregnadiene-11b,17a,21-triol-3,20-dione
CAS:50-24-8
EINECS:200-021-7
MF:C21H28O5
MW:360.44
MP:240oC(DEC.)
Density:1.28g/cm3
Assay:97.0%~102.0%
Quality Standards:BP2010/USP32/EP7
Storage:This product should be kept sealed in a cool and dry place.
Key words:Prednisolone 50-24-8 corticosteroid drug anti-inflammatory auto-immune

Uses:
Prednisolone is a corticosteroid drug with predominant glucocorticoid and low mineralocorticoid activity, making it useful for the treatment of a wide range of inflammatory and auto-immune conditions such as asthma uveitis, pyoderma gangrenosum, rheumatoid arthritis, ulcerative colitis, pericarditis, temporal arteritis and Crohn& acute;s disease, Bell& acute;s palsy, multiple sclerosis,cluster headaches, vasculitis, acute lymphoblastic leukemia and autoimmune hepatitis, systemic lupus erythematosus, Kawasaki disease and dermatomyositis. It is also used for treatment of sarcoidosis, though the mechanism is unknown.

Prednisolone acetate ophthalmic suspension (eye drops) is an adrenocortical steroid product, prepared as a sterile ophthalmic suspension and used to reduce swelling, redness, itching, and allergic reactions affecting the eye.

Prednisolone can also be used as an immunosuppressive drug for organ transplants and in cases of primary adrenal insufficiency (Addison& acute;s disease).

Corticosteroids inhibit the inflammatory response to a variety of inciting agents and, it is presumed, delay or slow healing. They inhibit the edema, fibrin deposition, capillary dilation, leukocyte migration, capillary proliferation, fibroblast proliferation, deposition of collagen, and scar formation with inflammation.

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