Biochemical
Description
Dextromethorphan Hydrobromide 125-69-9 Relieving cough
Name Dextromethorphan Hydrobromide
CAS 125-69-9
MF C18H26BrNO?
MW 352.31?
EINECS 204-750-1
Purity 99%
Appearance White crystalline powder
Storage Shading,?confined preservation
Usage Relieving cough and cold preparations
Categories API
Synonyms Dextromethorphan?maleate?HBR;?dextromethorphan?HBR;?(9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan?hydrobromide;?3-methoxy-17-methylmorphinan?hydrobromide;?(9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan?hydrobromide?hydrate;?Destromethorphan?hydrobromide
Use:
1. For dry cough, including upper respiratory tract infection (such as cold, pharyngitis, bronchitis, cough).
2. Research reagents, widely used in molecular biology, pharmacology research. This is the central antitussive, can inhibit the medulla cough centrum antitussive effect and produce. The antitussive effect is equal to or slightly. The general treatment dose not inhibit respiration, long-term use of no addiction and tolerance.
COA:?
?
Test Items Specification Test Results
Appearance white or almost white crystalline powder, slightly smelly white crystalline powder
Melting point 123~127oC 123~125oC
Specific Rotation +28°~+30° +29°
Acidity(PH) 5.2~6.5 5.8~6.2
Water 4.0%~5.5% 5.0%
Residue On Ignition Not more than 0.1% Conforms
N.N - dimethylaniline Comply with the standard Conforms
Phenolic Compounds Comply with the standard Conforms
Related Substance Comply with the standard Conforms
Assay Between99.0~102.0% 99.53%
Conclusion This batch is complies with USP 34.
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