Chemical Auxiliary
Description
Articaine hydrochloride 23964-57-0 Anesthetic
Product Name Articaine hydrochloride
CAS 23964-57-0
MF C13H20N2O3S.ClH
MW 320.839
EINECS 245-957-7
HS Code 3002909099
Purity 99%
Appearance White Crystalline Powder
Usage Anesthetic;Na+ channel inhibitor?
Categories local anesthetic;Pharmaceutical intermediate
Applications:
Articaine is a local anaesthetic that has been approved overseas for several years. Like other amide anaesthetics, articaine blocks nerve conduction when it is infiltrated around a nerve. This action is prolonged by combining the drug with a vasoconstrictor. The combination of articaine can be used for local or regional anaesthesia for dental procedures. Anaesthesia begins within six minutes and lasts for an hour. The half-life of articaine is approximately 1.8 hours. It is metabolised and then mainly excreted in the urine.
COA:
Items Specification Result
Description A white or almost white crystalline powder white crystalline powder
Solubility Freely soluble in water and in alcohol complies
Identification A,B,C,D complies
PH 4.2~5.2 4.90
Appearance
of solution
Related
substances Impurity A <0.2%;Any other
Impurity <0.1%;Total of other
Impurities<0.5%
Not detected ;0.08%;0.26%
Heavy metals <5ppm <5ppm
Loss on drying <0.5% 0.09%
Resiue on ignition <0.1% 0.09%
Organic residues complies complies
Assay 98.5%~101.05 99.6%
Conclusion complies
Use:
Articaine is used for pain control. Like other local anesthetic drugs, articaine causes a transient and completely reversible state of anesthesia (loss of sensation) during (dental) procedures. In dentistry, articaine is used both for infiltration and block injections, with the block technique yielding the greatest duration of anesthesia.
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