Pharmaceutical Products
Description
High Quality Methotrexate with Good Price
(CAS 59-05-2)
Quick Details:
Methotrexate CAS : 59-05-2 Brand: NEWBIO
MW: C20H22N8O5 MSDS: Avaiable
MF : 454.44 Sample: Avaiable
Category: Oncology drug Min order: 10grams
Quality standard: USP EP Place of Origin:China
Introduction used as anti-tumour medicament.
Character Orange-yellow ,crystalline powder
Applications Pharmaceutical raw materials , Oncology drug
Product Description:
Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate arrests the cell cycle in late G1/S-phase, therefore inhibiting the synthesis of DNA, RNA, thymidylates, and proteins. In the previous cases the inhibition of enzymes involved in purine metabolism, leading to accumulation of adenosine, or the suppression of intercellular adhesion molecule expression by T cells as the main mechanism of action by methotrexate. The compound has been observed to irreversibly inhibit dihydrofolate reductase (DHFR) and thymidylate synthetase (TS). Methotrexate has been shown to modulate inflammation by promoting adenosine release or inhibiting transmethylation reactions. In adherent splenic cells, IL-1 production was decreased by methorexate.
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Wuhan Biocar Bio-pharm Co., Ltd
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