Biochemical

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Tibolone

5630-53-5

Description

Quick Detail:
Product Name:Tibolone;Livial.
Alias:17β-Hydroxy-7α-methyl-19-nor-17α-pregn-5(10)-ene-20-yn-3-one
CAS: 5630-53-5
EINECS:227-069-1
Molecular Formula:C21H28O2
Molecular Weight:312.45
Assay: 99% min
Character: White Solid
Usage: Tibolone is a synthetic hormone derived from the Mexican yam.A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome
Description:
1). Tibolone is a synthetic steroid hormone drug, which is fairly non-selective in its binding profile, acting as an agonist mainly at estrogen receptors, with a preference for ER alpha. It is used mainly for treatment of endometriosis, as well as hormone replacement therapy in post-menopausal women. Tibolone has similar or greater efficacy compared to older hormone replacement drugs, but shares a similar side effect profile. It has also been investigated as a possible treatment for female sexual dysfunction.
2).Tibolone(Livial/Liviella) is used mainly for treatment of endometriosis, as well as hormone replacement therapy in post-menopausal women. Tibolone is a synthetic steroid hormone drug, which is fairly non-selective in its binding profile, acting as an agonist mainly at estrogen receptors, with a preference for ER alpha. Tibolone has similar or greater efficacy compared to older hormone replacement drugs, but shares a similar side effect profile. It has also been investigated as a possible treatment for female sexual dysfunction.
3). When estrogen levels are low tissues can slowly degenerate, as is experienced during menopause. In addition, low levels of estrogen can cause distressing symptoms such as hot flushes, night sweats, mood swings, reduced sex drive and vaginal dryness.Tibolone is broken down into three compounds which act in a similar way to the natural estrogen and progesterone found in the body.

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