Bio-technology Products
Description
600USD/IU.
Heparinase I (heparin lyase I) cleaves heparin and to a lesser extent heparan sulfate (ratio approx. 3:1).
Properties
Molecular weight: 42.8 kDa
Isoelectric point: 9.3 – 9.5
pH optimum for activity: 7.4
pH range for activity: 4 – 9
Optimal temperature range: 20 ℃ – 37 ℃
Purity: ≥ 98 % by reversed phase HPLC analysis
Protein impurities: < 0.1%
Specific Activity: > 400 IU/mg (max. 417 IU/mg)
Concentration: 10 IU/mL
Unit Definition: One international unit (IU) of heparinase I is defined as the amount of enzyme that will liberate 1.0 μmole unsaturated oligosaccharides from porcine mucosal heparin per minute at 35 ℃ and pH 7.0.
Stability: Expiration of heparinase I is 12 months from manufacturing date, frozen at -20 ℃ in PBS.
Applications
Heparinase I is useful in many applications (usually with heparinase II and heparinase III), for example:
For the neutralization of heparin in blood and plasma samples before analysis.
For similar in vitro neutralization of low molecular weight heparins.
As integral part of in vitro diagnostic tests for the neutralization of heparin (blood clotting tests, platelet tests).
In blood collection tubes for the neutralization of heparin.
For the preparation of low molecular weight heparins from unfractionated heparin.
As a research reagent (glycosaminoglycan degradation)
For the preparation of disaccharides of heparin and the preparation of oligosaccharide libraries.
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S-2238...
Beijing Adhoc International Technologies Co., Ltd
heparinase, heparin, thrombin, antithrombin
Address: No. 63, Maquanying Fourth Zone,Chaoyang District,
Beijing, Beijing
China, 100102
Tel: 86-10-562278774
Fax: 86-10-64321632
