Pharmaceutical Products
Description
1. Basic Information:
Product Name Lidocaine Hydrochloride
Synonym Lidocaine HCL,
CAS 73-78-9
MF C14H23ClN2O
MW 270.8
EINECS 200-803-8
Assay 99%
Quality Standards Enterprise Standard/Pharma Grade
Appearance White powder
1. Therapeutic actions:
(1) Type 1 antiarrhythmic: Decreases diastolic depolarization, decreasing automaticity of ventricular cells; increases ventricular fibrillation threshold.
(2) Local anesthetic: Blocks the generation and conduction of action potentials in sensory nerves by reducing sodium permeability, reducing height and rate of rise of the action potential, increasing excitation threshold, and slowing conduction velocity.
2. Indications:
(1) As antiarrhythmic: Management of acute ventricular arrhythmias during cardiac surgery and MI (IV use). Use IM when IV administration is not possible or when ECG monitoring is not available and the danger of ventricular arrhythmias is great (single-dose IM use, for example, by paramedics in a mobile coronary care unit)
(2) As anesthetic: Infiltration anesthesia, peripheral and sympathetic nerve blocks, central nerve blocks, spinal and caudal anesthesia, retrobulbar and transtracheal injection; topical anesthetic for skin disorders and accessible mucous membranes
3. Contraindications and cautions:
(1) Contraindicated with allergy to lidocaine or amide-type local anesthetics, CHF, cardiogenic shock, second- or third-degree heart block (if no artificial pacemaker), Wolff-Parkinson-White syndrome, Stokes-Adams syndrome.
(2) Use cautiously with hepatic or renal disease, inflammation or sepsis in the region of injection (local anesthetic), labor and delivery (epidural anesthesia may prolong the second stage of labor; monitor for fetal and neonatal CV and CNS toxicity), and lactation.
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Shenzhen SMQ Bio-tech Co., Ltd.
Steroid powder,cinnamate acid ,pharmaceutical raw material
Address: #2 New District Road, Minzhi Street, Longhua New District,
Shenzhen, Guangdong
China, 518131
Tel: 0755-88320842
Fax:
