Pharmaceutical Products
Description
1. Basic Information:
Product Name Proparacaine Hydrochloride
Synonym Proparacaine HCL, Chibro-Heracaine, Alcaine
CAS 5875-06-9
MF C16H27ClN2O3
MW 330.85
EINECS 227-541-7
Assay 99%
Quality Standards Enterprise Standard/Pharma Grade
Appearance White powder
2. Clinical Pharmacology:
(1) Proparacaine Hydrochloride Ophthalmic Solution is a rapid acting local anesthetic suitable for ophthalmic use. With a single drop, the onset of anesthesia begins within 30 seconds and persists for 15 minutes or longer.
(2) The main site of anesthetic action is the nerve cell membrane where proparacaine interferes with the large transient increase in the membrane permeability to sodium ions that is normally produced by a slight depolarization of the membrane. As the anesthetic action progressively develops in a nerve, the threshold for electrical stimulation gradually increases and the safety factor for conduction decreases; when this action is sufficiently well developed, block of conduction is produced.
3. Indications and Usage:
Proparacaine hydrochloride ophthalmic solution is indicated for topical anesthesia in ophthalmic practice. Representative ophthalmic procedures in which the preparation provides good local anesthesia include measurement of intraocular pressure (tonometry), removal of foreign bodies and sutures from the cornea, conjunctival scraping in diagnosis and gonioscopic examination; it is also indicated for use as a topical anesthetic prior to surgical operations such as cataract extraction.
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Shenzhen SMQ Bio-tech Co., Ltd.
Steroid powder,cinnamate acid ,pharmaceutical raw material
Address: #2 New District Road, Minzhi Street, Longhua New District,
Shenzhen, Guangdong
China, 518131
Tel: 0755-88320842
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